Nitroblue tetrazolium reduction. False positive and false negative results.

Quantitative and histochemical nitroblue with polycythemia vera and neoplasia astetrazolium reduction (NBT) tests were persociated with fever, as well as in those with formed on leukocytes of 13 patients with known bacterial infection. It is suggested polycythemia vera, seven with chronic that patients with neoplasia or polycygranulocytic leukemia, eight with neothemia vera may show a false positve plastic disease associated with fever, 16 reaction in the histochemical NBT test. with bacterial infection, and 13 healthy Conversely, the test was significantly lower control individuals. No significant differthan control in patients with chronic granences were detected in the quantitative ulocytic leukemia. Such patients might test between any of the groups studied. show a false negative reaction in the test The histochemical NBT test was signifeven if infection were present. icantly higher than control in the patients